About Apex

Engineering the future of spine surgery.

Apex Orthopaedic Technologies develops clinically driven spine technologies through biomechanics, engineering, and translational research. Built by physicians, engineers, and scientists committed to solving some of spine surgery's most challenging clinical problems.

Anatomical illustration of a human spine

Our Story

From an unmet clinical need to an integrated technology platform.

Medical University of South Carolina campus along the Charleston waterfront — the academic origin of Apex Orthopaedic Technologies

Apex Orthopaedic Technologies was founded in Charleston, South Carolina, and emerged from a long-standing collaboration between the Medical University of South Carolina (MUSC) and Clemson University focused on translating clinically driven engineering into innovative spine technologies. The company began with a single clinical problem that conventional spinal implants could not adequately solve, leading to the development of a fundamentally new approach to spinal fixation that ultimately became the R-FIX™ platform.

What began as an academic collaboration has evolved into a multidisciplinary spine technology company dedicated to translating clinically driven engineering into technologies that improve patient care. Today, Apex develops integrated technology platforms spanning pediatric spinal deformity, adult spinal deformity, sacroiliac fusion, posterior fixation, biomechanics, surgical navigation, digital health, and translational medical device development.

Headquartered in Charleston, South Carolina, Apex continues to collaborate closely with leading surgeons, engineers, physician-scientists, academic institutions, and industry partners to accelerate the translation of innovative technologies from concept to clinical practice.

Our mission is not simply to develop implants, but to solve meaningful clinical problems through engineering, scientific validation, and collaboration.

Our Mission

To solve some of spine surgery's most challenging clinical problems through engineering, biomechanics, and scientific validation.

We strive to bridge academic innovation and commercial translation by developing technologies that improve patient care around the world.

Development Philosophy

A disciplined path from clinical need to patient impact.

Every Apex technology follows the same disciplined development pathway — from identifying an unmet clinical need through rigorous engineering and scientific validation before reaching clinical practice.

Step 01

Clinical Need

Step 02

Engineering Innovation

Step 03

Scientific Validation

Step 04

Clinical Translation

Step 05

Patient Impact

What Makes Apex Different

Four principles that define how we build.

Clinically Driven

Every technology begins with an unmet clinical need identified by practicing surgeons.

Engineering Excellence

Biomechanics, computational modeling, and thoughtful engineering guide every stage of development.

Scientific Validation

Finite element analysis, mechanical testing, cadaver evaluation, animal studies, and clinical research support every technology.

Collaborative Innovation

Apex brings together physicians, engineers, scientists, academic institutions, and industry partners to accelerate innovation.

Leadership

Multidisciplinary leadership across engineering, medicine, and science.

Daniel Bonthius, MD, PhD

Founder & Chief Executive Officer

Daniel Bonthius, MD, PhD

Physician-engineer with expertise in emergency medicine, orthopedics, biomedical engineering, biomechanics, and translational medical device development. Leads Apex's corporate strategy, product development, intellectual property, regulatory planning, commercialization, fundraising, and strategic partnerships.

Hai Yao, PhD

Co-Founder & Chief Scientific Officer

Hai Yao, PhD

Associate Vice President for Biomedical Innovation, Professor and Ernest R. Norville Endowed Chair, and Associate Chair for the CU-MUSC Bioengineering Program. Internationally recognized expert in musculoskeletal biomechanics, computational modeling, implant design, and translational orthopaedic research.

Joe Powers

President

Joe Powers

Leads business operations, commercialization strategy, and corporate growth initiatives. Former VP of Marketing at market leader SI-BONE.

Marc Yap

Chief Technology Officer

Marc Yap

Leads engineering strategy, product development, manufacturing, and technology commercialization. Brings engineering experience at multiple SI companies, including SI-BONE.

Stephen Kalhorn, MD

Chief Medical Officer

Stephen Kalhorn, MD

Professor of Neurosurgery at MUSC, Director of Spine Surgery, and Director of the Spine CAST Fellowship. Provides clinical leadership across Apex technologies.

Mike Wentz

Director of Operations

Mike Wentz

Supports organizational development, operational growth, internal company operations, and investor relations. An engineer who formerly worked at Ellipse Technologies developing the MAGEC Growing Rod System, later acquired by NuVasive/Globus.

Scientific Advisory Board

Guided by leading voices in spine surgery and biomechanics.

Choll Kim, MD

Minimally Invasive Spine

Choll Kim, MD

Minimally Invasive Spine Surgeon, Excel Spine

Peter Whang, MD

Adult Spine & SI Fusion

Peter Whang, MD

Professor, Department of Orthopaedics and Rehabilitation, Yale University School of Medicine

Vikas Patel, MD

Adult Spinal Deformity

Vikas Patel, MD

Executive Vice Chair, Orthopedic Surgery, University of Colorado School of Medicine

Alaa Ahmad, MD

Pediatric Spine

Alaa Ahmad, MD

International Pediatric Orthopedic Surgeon

Behrooz Akbarnia, MD

Pediatric & Adult Deformity

Behrooz Akbarnia, MD

Founder and Board Chairman, San Diego Spine Foundation

Academic & Clinical Collaborators

Collaboration accelerates rigor and translation.

Medical University of South Carolina logoMedical University of South Carolina
Clemson University logoClemson University
Atrium Health / Wake Forest University School of Medicine logoAtrium Health / Wake Forest University School of Medicine
Yale University logoYale University
University of Colorado Anschutz Medical Campus logoUniversity of Colorado Anschutz Medical Campus

Recognition & Milestones

Independent validation of Apex's engineering and science.

FDA Breakthrough Device Designation

Competitive NIH Funding

>$4M non-dilutive

NASS Young Investigator Award

2024 · 2025

InnoVision Technology Development Award

2024

ORS Business Innovation Competition

Runner-Up · 2022

ORS Spine Section Podium Award

2020

SC Research Society Innovator of the Year

Finalist · 2025

SC Research Authority Researcher of the Year

Finalist · 2024

Issued & Pending Patent Portfolio

Apex Through the Years

The visual story of a growing spine technology company.

Apex Team
The Apex team gathered together.
NASS Award
Recognition at the North American Spine Society meeting.

Building What's Next

The next generation of spine technologies.

Apex continues to develop the next generation of spine technologies through engineering excellence, scientific rigor, and close collaboration among surgeons, scientists, and industry partners. Our vision is to transform important clinical ideas into technologies that improve patient care worldwide.